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4 edition of Role of ethanol tolerance in alcohol consumption found in the catalog.

Role of ethanol tolerance in alcohol consumption

Harish Sharma

Role of ethanol tolerance in alcohol consumption

by Harish Sharma

  • 95 Want to read
  • 22 Currently reading

Published by National Library of Canada in Ottawa .
Written in English


Edition Notes

SeriesCanadian theses = Thèses canadiennes
The Physical Object
FormatMicroform
Pagination2 microfiches.
ID Numbers
Open LibraryOL18682164M
ISBN 100315565527
OCLC/WorldCa24906886

Ethanol with the molecular formula C2H6O is a clear, colorless, volatile liquid with a pleasant smell made by fermentation of sugar. Ethanol is one of many kinds of alcohol and is the only type of alcohol that can be consumed. Apart from consumption, ethanol is used for several other purposes such as fuel to power engines, as a disinfectant (because of its bactericidal activity), as a solvent. Ethanol, or ethyl alcohol, is a type of alcohol, which is a hydrocarbon with one or more hydroxyl (-OH) groups substituted in place of one or more hydrogen atoms. Methanol and propanol are other common alcohols. Ethanol is a versatile molecule used in beverages and as a component of fuels.

  INTRODUCTION. Alcohol is one of the most widely used and abused drugs contributing to a variety of medical and socio-economic problems (US Public Health Service, ).Chronic excessive intake of ethanol (EtOH) for long periods causes development of tolerance to and dependence on by: ISBN: OCLC Number: Description: pages: illustrations ; 25 cm. Contents: Alcohol-related nutrition derangements: implications for nutritional support / Olalekan E. Odeleye and Ronald R. Watson --Dietary factors and alcohol consumption / Raye Z. Litten and John P. Allen --Nutritional status of alcoholics from different social groups / Mikko Salaspuro.

  Turning Fuel Ethanol Into Beverage Alcohol Date: with the same care and purity as alcohol for consumption, he said. one large producer of ethanol and food-grade alcohol interested in . Pregnant or lactating women, anyone under legal drinking age (children and adolescents), individuals taking medications that interact with alcohol, those with specific medical conditions, those engaging in activities that require attention, skill, or coordination (driving), those who cannot restrict alcohol intake.


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Role of ethanol tolerance in alcohol consumption by Harish Sharma Download PDF EPUB FB2

Doodipala Samba Reddy, in Progress in Brain Research, Alcohol withdrawal. Neurosteroids play an important role in alcohol tolerance and withdrawal (Morrow et al.,; Romeo et al., ).There is an essential correlation between the time course of ethanol-induced allopregnanolone production in the brain and specific behavioral and neural effects of ethanol.

Steven N. Treistman, Garrett E. Seale, in Neurobiology of Alcohol Dependence, Ethanol Regulation of Gene Transcription. An important component of our understanding of molecular alcohol tolerance will require an understanding at the DNA level.

Although this topic is covered more extensively in other chapters in this book, we will briefly examine how one specific transcription factor, CREB. Hence, a selective increase in SLO-1 channel activity could recapitulate behavioral effects of ethanol.

Although the role of BK channel activation in ethanol intoxication in mammals is not fully understood, similar ethanol-induced increases in the frequency of opening of mammalian BK channels have been observed in vitro (Dopico et al., ).

When you ingest alcohol in a fasting state, how long does it take for the alcohol to reach peak blood concentrations 30 mins what are 3 reasons why alcohol/ethanol is easily. A Role for Dynamin in Triggering Ethanol Tolerance.

by which alcohol consumption produces changes in gene expression remain poorly understood. and functionally test the element for a role. Alcohol tolerance is on the rise. Alcohol is the most frequently consumed type of drink other than the carbonated soft beverages.

In fact, alcohol is the number one drink in some countries. Unfortunately, alcohol is an intoxicating beverage which produces effects that vary from excitement to narcosis, depending on the individual tolerance and the amount : Marixie Ann Manarang-Obsioma.

Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is a chemical compound, a simple alcohol with the chemical formula C 2 H 6 formula can be also written as CH 3 − CH 2 − OH or C 2 H 5 OH (an ethyl group linked to a hydroxyl group), and is often abbreviated as l is a volatile, flammable, colorless liquid with a slight characteristic odor.E number: E (additional chemicals).

Endocannabinoid signaling plays the important role in regulation of ethanol intake. Fatty acid amide hydrolase (FAAH) is a key membrane protein for metabolism of Cited by: This is the role that the liver plays in the development of alcohol tolerance.

The brain also has a role in the development of alcohol tolerance. When the neurotransmitter systems in the brain are regularly exposed to large amounts of alcohol they begin to adapt to the presence of alcohol.

Rather if tolerance has a role in facilitating increased consumption, loss of control and inability to remain abstinent, the tolerance to the aversive responses to alcohol could be involved. Tolerance has been shown to conditioned place aversion and conditioned taste aversion.

The relationship between sleepiness-alertness and alcohol consumption, however, may be bidirectional. Thus, some survey and laboratory data suggest that variations in the duration of nocturnal sleep and level of day-time sleepiness may play an important role in modulating alcohol consumption.

Alcohol, gender and drinking problems: perspectives from low and middle income countries. Alcohol drinking - adverse effects 2. Chapter 2: Social consequences of alcohol consumption growing role of alcohol in global public health, especially in developing countries, and the need for more funding to continue some of the World File Size: 2MB.

Mice deficient for the intracellular protein Fyn tyrosine kinase (fynZ/fynZ mice) have been reported to show increased alcohol sensitivity and lack of tolerance to the effects of ethanol.

The development of tolerance to ethanol was examined in two rat lines selected for high (AA) and low (ANA) ethanol consumption. In the first experiment, the acquisition of tolerance to the motor-impairment, hypothermic and hypnotic effects of ethanol produced by daily treatment with 5 g/kg ethanol for a period of 24 days was examined.

Tolerance to these effects of ethanol was observed in Cited by: Tabakoff B., Ritzmann R.F., Hoffman P.L. () Role of Catecholamines in the Development of Tolerance to Barbiturates and Ethanol. In: Gross M.M. (eds) Alcohol Intoxication and Withdrawal—IIIb.

Advances in Experimental Medicine and Biology, vol by: Studies comparing the pattern of intragastric ethanol self-infusion in alcohol-dependent inbred mice have also shown that DBA/2 mice (which normally avoid ethanol in oral consumption studies) will administer a greater portion of their daily intakes in larger magnitude bouts than alcohol-preferring C57BL/6 mice, suggesting that dependent DBA/2 Cited by: Alcohol, sometimes referred to by the chemical name ethanol, is a psychoactive drug that is the active ingredient in drinks such as beer, wine, and distilled spirits (hard liquor).

It is one of the oldest and most common recreational substances, causing the characteristic effects of alcohol intoxication ("drunkenness").

Among other effects, alcohol produces a mood lift and euphoria, decreased Pregnancy category: US: C (Risk not ruled out). Ethanol is a widely used drug whose mechanism of action, despite intensive study, remains uncertain.

Biochemical and electrophysiological experiments have identified receptors and ion channels whose functions are altered at physiological concentrations of ethanol. Yet, the contribution of these potential targets to its intoxicating or behavioral effects is unclear.

"Alcohol consumption is influenced by a combination of environmental and genetic factors," said Gene Erwin, Ph.D., professor of pharmaceutic sciences at the CU School of Pharmacy, "This study indicated that genetic factors play more of a role, and we're trying to understand the power of those genetic factors.".

Treatments that Reduce 5-HT Function and Other Drug-Reinforced Behaviour -- III. Biochemical Factors -- IV. Summary -- D. 5-HT, Alcohol Tolerance, and Physical Dependence -- I. General Aspects of Alcohol Tolerance -- 1.

Definition and Classification -- 2. Features of Ethanol Tolerance -- II. Role of 5-HT in Ethanol Tolerance\/Dependence -- III.

changes occur as the development of tolerance to alcohol’s effects. When alcohol consumption is abruptly discontinued or reduced, these compensatory changes are no longer opposed by the presence of alcohol, thereby leading to the excitation of neurotransmitter systems and the development of alcohol withdrawal syndrome.

Long-term alcohol File Size: KB. Ethanol is a psychoactive substance causing both short- and long-term behavioural changes in humans and animal models.

We have used the fruit fly Drosophila melanogaster to investigate the effect of ethanol exposure on the expression of the Gαq protein subunit. Repetitive exposure to ethanol causes a reduction in sensitivity (tolerance) to ethanol, which we have measured as the time Author: Benjamin Aleyakpo, Oghenetega Umukoro, Ryan Kavlie, Daniel C.

Ranson, Andrew Thompsett, Andrew Thomp. The book says alcohol is often viewed only as a "social problem" or as a means to get drunk—but this overlooks its importance in the social fabric .